This Error event may be triggered by multiple causes. Similarly, the method by which you resolve this error varies greatly depending on what triggered this event in your Exchange organization. This Error event may be accompanied by MSExchangeSA error event 2035 or MSExchangeAL error events 8325, 8231, and 8357.

To resolve this error, do one or more of the following:

• Review the System and Application event logs for related events. For example, events that occur immediately before and after this event may provide more information about the root cause of this error.
  
  
• If the Application event log has MSExchangeSA Error event 2035, uninstall the third-party application referenced in the Error event. Exchange 2010 does not support third-party 32-bit applications, and attempting to install them will result in failure because they do not include a 64-bit address generator.
  
  

If you cannot resolve this error, or you experience other problems or mail flow interruptions in your Exchange environment after attempting to resolve this error, contact Microsoft Product Support. For information about contacting support, visit the Contact Us page of the Microsoft Help and Support Web site.

If you are not already doing so, consider running the Exchange tools created to help you analyze and troubleshoot your Exchange environment. These tools can help make sure that your configuration aligns with Microsoft best practices. They can also help you identify and resolve performance issues, improve mail flow, and better manage disaster recovery scenarios. To run these tools, go to the Toolbox node of the Exchange Management Console. To learn more about these tools, see Managing Tools in the Toolbox.